I am interested in understanding complex biological features by the integration of big data coming from approaches such as ‘-omic’ methodologies with the aim of providing new biotechnological and biomedical applications. This has motivated me to gain expertise in different fields, including bioinformatics, systems biology, artificial intelligence, data analysis, and synthetic biology.
Publications
2022. A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications.  Nat Commun 13(1):1910
,2021. LoxTnSeq: random transposon insertions combined with cre/lox recombination and counterselection to generate large random genome reductions.  Microb Biotechnol 14(6):2403-2419
,2020. FASTQINS and ANUBIS: two bioinformatic tools to explore facts and artifacts in transposon sequencing and essentiality studies.  Nucleic Acids Res 48(17):e102
,2020. Inferring Active Metabolic Pathways from Proteomics and Essentiality Data.  Cell Rep 31(9):107722
,2019. The role of clonal communication and heterogeneity in breast cancer.  BMC Cancer 19(1):666
,2019. SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes.  DNA Res 26(4):327-339
,2019. Unraveling the hidden universe of small proteins in bacterial genomes.  Mol Syst Biol 15(2):e8290
,2017. Alternative transcriptional regulation in genome-reduced bacteria.  Curr Opin Microbiol 39:89-95
,2016. High frequencies of antibiotic resistance genes in infants' meconium and early fecal samples.  J Dev Orig Health Dis 7(1):35-44
,2014. Engineering bacteria to form a biofilm and induce clumping in Caenorhabditis elegans.  ACS Synth Biol 3(12):941-3
,Publication list retrieved from NCBI using ImpactPubs
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