Bioinformatics, systems biology, artificial intelligence, data analysis, and synthetic biology.
Publications
2024. ProTInSeq: transposon insertion tracking by ultra-deep DNA sequencing to identify translated large and small ORFs.  Nat Commun 15(1):2091
,2022. robustica: customizable robust independent component analysis.  BMC Bioinformatics 23(1):519
,2022. SURE editing: combining oligo-recombineering and programmable insertion/deletion of selection markers to efficiently edit the Mycoplasma pneumoniae genome.  Nucleic Acids Res 50(22):e127
,2022. Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision.  Proc Natl Acad Sci U S A 119(29):e2117090119
,2022. A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications.  Nat Commun 13(1):1910
,2021. LoxTnSeq: random transposon insertions combined with cre/lox recombination and counterselection to generate large random genome reductions.  Microb Biotechnol 14(6):2403-2419
,2020. FASTQINS and ANUBIS: two bioinformatic tools to explore facts and artifacts in transposon sequencing and essentiality studies.  Nucleic Acids Res 48(17):e102
,2020. Inferring Active Metabolic Pathways from Proteomics and Essentiality Data.  Cell Rep 31(9):107722
,2019. The role of clonal communication and heterogeneity in breast cancer.  BMC Cancer 19(1):666
,2019. SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes.  DNA Res 26(4):327-339
,2019. Unraveling the hidden universe of small proteins in bacterial genomes.  Mol Syst Biol 15(2):e8290
,2017. Alternative transcriptional regulation in genome-reduced bacteria.  Curr Opin Microbiol 39:89-95
,2016. High frequencies of antibiotic resistance genes in infants' meconium and early fecal samples.  J Dev Orig Health Dis 7(1):35-44
,2014. Engineering bacteria to form a biofilm and induce clumping in Caenorhabditis elegans.  ACS Synth Biol 3(12):941-3
,Publication list retrieved from NCBI using ImpactPubs
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