My current research focuses on exploring different aspects of translation regulation as well as protein degradation pathways in the minimal cell model M. pneumoniae. As a member of the team of the MycoSynVac project, I am also involved in the design of a mycoplasma chassis optimized to grow faster in bioreactors, a requirement to create a cost-effective product in industry. To do so, we are rationally modifying its genome in combination with the establishment of a serum-free medium.

Publications

Burgos R; Wood GE; Iverson-Cabral SL; Totten PA, 2018. Mycoplasma genitalium Nonadherent Phase Variants Arise by Multiple Mechanisms and Escape Antibody-Dependent Growth Inhibition.  Infect Immun 86.

Burgos R; Totten PA, 2014. MG428 is a novel positive regulator of recombination that triggers mgpB and mgpC gene variation in Mycoplasma genitalium.  Mol Microbiol 94(2):290-306

Burgos R; Totten PA, 2014. Characterization of the operon encoding the Holliday junction helicase RuvAB from Mycoplasma genitalium and its role in mgpB and mgpC gene variation.  J Bacteriol 196(8):1608-18

Burgos R; Wood GE; Young L; Glass JI; Totten PA, 2012. RecA mediates MgpB and MgpC phase and antigenic variation in Mycoplasma genitalium, but plays a minor role in DNA repair.  Mol Microbiol 85(4):669-83

Pich OQ; Burgos R; Querol E; Piñol J, 2009. P110 and P140 cytadherence-related proteins are negative effectors of terminal organelle duplication in Mycoplasma genitalium.  PLoS One 4(10):e7452

Pich OQ; Burgos R; Ferrer-Navarro M; Querol E; Piñol J, 2008. Role of Mycoplasma genitalium MG218 and MG317 cytoskeletal proteins in terminal organelle organization, gliding motility and cytadherence.  Microbiology 154(Pt 10):3188-98

Burgos R; Pich OQ; Querol E; Piñol J, 2008. Deletion of the Mycoplasma genitalium MG_217 gene modifies cell gliding behaviour by altering terminal organelle curvature.  Mol Microbiol 69(4):1029-40

Burgos R; Pich OQ; Querol E; Piñol J, 2007. Functional analysis of the Mycoplasma genitalium MG312 protein reveals a specific requirement of the MG312 N-terminal domain for gliding motility.  J Bacteriol 189(19):7014-23

Burgos R; Pich OQ; Ferrer-Navarro M; Baseman JB; Querol E; Piñol J, 2006. Mycoplasma genitalium P140 and P110 cytadhesins are reciprocally stabilized and required for cell adhesion and terminal-organelle development.  J Bacteriol 188(24):8627-37

Pich OQ; Burgos R; Ferrer-Navarro M; Querol E; Piñol J, 2006. Mycoplasma genitalium mg200 and mg386 genes are involved in gliding motility but not in cytadherence.  Mol Microbiol 60(6):1509-19

Pich OQ; Burgos R; Planell R; Querol E; Piñol J, 2006. Comparative analysis of antibiotic resistance gene markers in Mycoplasma genitalium: application to studies of the minimal gene complement.  Microbiology 152(Pt 2):519-27

Publication list retrieved from NCBI using ImpactPubs

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