Bioinformatics, protein structure, protein design, C++, FoldX, data analysis.
Bio
After graduating in a Chemistry high school in 2012 I enrolled in the Molecular Biology bachelor at University of Padua (Italy). I graduated in 2016 carrying my bachelor thesis in the Bioinformatics Lab. of Professor Chiara Romualdi, combining my studies with the passion for computers and programming. There I became aware of the “Two years Bologna Master in Bioinformatics” which I concluded with the highest grade in July 2018, with a thesis entitled “Target driven engineering of DNA-Protein interfaces” performed in Luis Serrano Lab. at CRG of Barcelona, under the supervision of two worldwide renowned experts on structural Bioinformatics: Prof. Luis Serrano Pubul and Prof. Rita Casadio (Alma Mater Studiorum – Bologna). Later that year, a Bioinformatician position was offered to me by Prof. Serrano to further develop and use ModelX and FoldX; two well established software for the generation, engineering and evaluation of bio-molecular structural models. In September 2019 I have been awarded with a prestigious fellowship from “la Caixa” foundation to develop a PhD entitled “In silico biomolecular engineering with FoldX and ModelX”.
Publications
, 2022. Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision. Proc Natl Acad Sci U S A 119(29):e2117090119
, 2020. In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species. PLoS Comput Biol 16(12):e1008450
, 2020. ProteinFishing: a protein complex generator within the ModelX toolsuite. Bioinformatics 36(14):4208-4210
, 2019. Protein-assisted RNA fragment docking (RnaX) for modeling RNA-protein interactions using ModelX. Proc Natl Acad Sci U S A 116(49):24568-24573
, 2019. FoldX 5.0: working with RNA, small molecules and a new graphical interface. Bioinformatics 35(20):4168-4169
Publication list retrieved from NCBI using ImpactPubs
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